Research

The evidence, and
the proof.

Two questions decide whether a creatine is worth taking: does the molecule work, and is the powder in the tub actually what it claims? The first is answered by four decades of published science. The second is answered by the Crealean® certificate.

The molecule

Backed by the literature.

Creatine monohydrate is the most-researched supplement in sports science — the rare case where the evidence arrived before the hype.

#1most-researched sports supplement in the world
1,000+peer-reviewed studies published
40+ yrsof documented research and use
1ingredient — nothing to look up but purity

What the science says

Six areas, plainly summarized.

A tour of where the research on creatine is strongest — and where it’s still being written.

R.01Strength & power

Consistently improves maximal strength

Across decades of trials, adding creatine to resistance training reliably increases strength and power output beyond training alone — the effect the research is most confident about.

R.02Lean mass

Supports gains in muscle size

By enabling more quality training volume and improving cell hydration, creatine is associated with greater increases in lean body mass over a training block.

R.03Repeated efforts

Boosts repeated-sprint performance

Studies of short, maximal, repeated efforts show less drop-off between bouts — directly relevant to team and field sports.

R.04Recovery

May aid recovery between sessions

Evidence points to reduced markers of muscle damage and faster restoration of energy stores when creatine is taken consistently.

R.05Brain & cognition

A growing area of study

Because the brain runs on the same ATP system, researchers are actively studying creatine for cognition under fatigue, sleep deprivation, and healthy aging.

R.06Safety

A strong long-term safety record

Creatine monohydrate is among the most-studied supplements in existence, with a large body of evidence supporting daily use in healthy adults.

These are plain-language summaries of the published literature on creatine monohydrate, provided for education. They are not medical advice — if you have a health condition or take medication, talk to your doctor before supplementing.

Effect ranges quoted across this site summarise the published literature on creatine monohydrate — principally the International Society of Sports Nutrition position stand on creatine supplementation (Kreider et al., Journal of the International Society of Sports Nutrition, 2017) and the trials and systematic reviews it reviews. Figures are typical reported ranges across study populations, not a promise of individual results.

The research behind the mark

How Crealean is verified.

Great research on creatine is worthless if the powder in the tub isn’t the real thing. Here’s the testing that stands behind the trademark.

/ 01Assay

Creatine content by HPLC

Each batch is assayed by high-performance liquid chromatography to confirm it meets the 99.99% purity the label claims.

/ 02Screen

Contaminant screening

We screen for the by-products that separate premium creatine from commodity powder — dicyandiamide, dihydrotriazine — plus heavy metals.

/ 03Size

Particle-size verification

Micronization is checked against a 200-mesh standard so every tub disperses clean rather than settling into grit.

/ 04Trace

Certificate for every batch

Results are recorded against a batch code printed on the tub — the certificate of analysis is the mark's proof, not a marketing line.

Sample batch reference: CRL-2408-99A · assayed at 99.99%.

Proof, not promises

Read the mark, not the marketing.

See what Crealean® stands for and how to put it to work.

About the trademark